Diamond Light Source (Diamond) and the Structural Genomic Consortium (SGC) Oxford announced today that Enamine will become a key supplier of poised fragment and analogue libraries to its XChem facility. Enamine will offer a new generation of the hit-finding library, Diamond-SGC-iNEXT (DSI) Poised Library to enable fast and productive fragment-based lead discovery (FBLD).
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Axxam S.p.A. and Enamine Ltd. announced the start of a Research Collaboration to enhance the Axxam small molecule screening library with the addition of a further set of compounds aimed at early-stage CNS drug discovery, achieving a total library size of ca. 280 000 compounds.
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Enamine Ltd. and the European Molecular Biology Laboratory (EMBL) have agreed to establish a collaboration whereby Enamine provides library synthesis, medicinal chemistry and biological services for the discovery and development of novel small molecules against EMBL’s proprietary anti-cancer targets.
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Enamine Ltd. has announced that it has agreed to expand its collaboration in early drug discovery with Actelion Pharmaceuticals, covering therapeutic areas including cardiovascular and central nervous system disorders, immunology, infectious diseases and oncology.
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EnamineStore expands its e-commerce functionality: online access to safety and analytical data on purchased compounds; requesting analogues; getting online quotes; automated order processing and more arrivals Read more...

Enamine Ltd., a chemical company, producer of building blocks and screening libraries, announced today that it had signed a collaboration agreement with small molecule design house FCH Group Ltd (FCH).
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This year Enamine celebrates 25 years of excellence in chemistry. In commemoration of this special event, we have launched a total discount program at EnamineStore.com. Please visit our online shop and apply for exceptional 25% discount for 160 000+ building blocks, 2 100 000+ screening compounds and 50 000+ fragments in stock.

Upon confirmation, your profile at EnamineStore will be granted with 25% discount that will be further automatically applied to all your online purchases made until October 31, 2016.

Hurry up! The program has just started today and the clock is ticking for this exclusive offer!

Announced on 1^st March, 2016 ChemSpace, a global e-procurement marketplace for searching, purchasing and selling chemical building blocks, has already accumulated over 20 million unique reagents and become the world’s largest pool of purchasable building blocks for medicinal chemistry. ChemSpace’s powerful engine supports storage and operations with millions of chemical entries. The platform sets no limits for suppliers and thus provides access to the most actual information on innovative molecules that have just appeared on the market.

Enamine, ChemBridge Corporation, UORSY and FCH Group today announced launch of Chem-Space, a global e-procurement marketplace solution for searching, purchasing and selling chemical building blocks. The Chem-Space database currently encompasses over 15 million unique molecular building blocks, and is the world’s largest chemicals library.
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Enamine is announcing today the expansion of its Purification and Analytical Units to enable synthesis of 30 000 high quality screening library compounds monthly. Such expansion represents the largest development to date of its library synthesis capabilities.
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Reactions conducted in autoclaves are very popular at Enamine because they allow synthesis of unique and novel building blocks that would not be doable otherwise. The key to their successful implementation into every day’s routine are quality pressure reactors that offer safe operations and are inexpensive at the same time.

Enamine is organizing a research workshop within a framework of the company’s participation in a HORIZON-2020 project. The workshop will be held on June 17-19, 2017 in a hotel “Rus” under the supervision of Prof. I.V.Komarov.

Enamine is proud to announce that it has expanded its building blocks storage facility in Cincinnati totaling now 72 000 compounds. This allows Enamine to expedite logistics with its numerous US customers, offering a next-day delivery option for the majority of orders.

Enamine Ltd. and Danish biotech company Pcovery have announced that they have extended their collaboration for the discovery of new drugs for the treatment of invasive fungal infections and platform technology development.
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Enamine is announcing the expansion of its building blocks storage in its Cincinnati, logistic center, reaching currently more than 50 000 novel substances, with the plan to reach through its continued efforts at least 60 000 building blocks until the end of 2016. The company fulfills in this way the request of its numerous USA customers to expedite delivery time and fasten projects start.

Dr. Pavel MYKHAILIUK, CSO at Enamine, has become a finalist at European Young Chemist Award 2016. He gave a talk at 6th EuCheMS Chemistry Congress (Seville, Spain, September 11-15). The European Young Chemist Award 2016 is intended to showcase and recognise the excellent research being carried out by young scientists working in the chemical sciences.

Enamine announces the launch of a mobile version of EnamineStore catalog of building blocks and screening compounds. Realizing the growing number of mobile internet users among our customers, we have developed EnamineStore Mobile^Beta which is optimized for smartphones and tablet PCs. We hope it will further improve catalog browsing and shopping experience for our customers and stimulate the use of new mobile technologies to access our website.

Please, read more at our blog and explore EnamineStore Mobile for yourself.

Please, send your valuable feedback to This email address is being protected from spambots. You need JavaScript enabled to view it.

Enamine Ltd, together with Elsevier, ChemSpace SIA, Institute of Organic Chemistry of National Academy of Sciences of Ukraine, and Kyiv Institute of Bioorganic Chemistry and Petrochemistry of National Academy of Sciences of Ukraine, are co-organizing The 18th European Symposium on Fluorine Chemistry to be held on August 7 - 12, 2016 in Hotel Ramada Encore Kyiv, Ukraine. Early bird registration for the event is now open for industrial and academic participants from around the world. Student participation is possible.

This year’s Symposium is a continuation of a long tradition of gathering research and industrial leaders in the field of fluorine science from all around the globe in order to discuss modern trends in fluorine research, present latest achievements and breakthroughs. The scope of the event will include application of fluorine in areas of drug discovery, material science, agrochemistry, energy storage and many others.

The main sub-sections are as following:

• Organic and Bio-Organic Fluorine Chemistry,
• Inorganic Fluorine Chemistry,
• Physical Fluorine Chemistry
• Industrial and Polymer Fluorine Chemistry.
• Other Areas of Fluorine Science

All interested industrial and academic organizations, individual scientists and students are welcome to register for participation in this year’s leading event on Fluorine.

Nature Scientific Report “Identification of potential inhibitors based on compound proposal contest: Tyrosine-protein kinase Yes as a target”

Compound proposal contest has been held at Tokyo Institute of Technology (Japan) on January 7 - March 20 2014 in a form of open innovation competition. Organized by the Initiative for Parallel Bioinformatics (IPAB) and supported by Enamine, it was aimed at identification of novel approaches for Computer Aided Drug Discovery (CADD) and finding novel unique hit molecules.

Enamine provided its world’s largest Screening Collection as a source of diverse compounds for the contest participants, who were instructed to select a maximum of 1 200 prioritized compounds towards a specific biological target - Tyrosine-protein kinase Yes. The contest resulted into 600 unique molecules selected by jury, from which 27 inhibitors were identified, yielding finally 7 potential hits.

Enamine’s Screening Compounds Collection is a unique product offering containing more than 2 000 000 diverse and distinct compounds in significant amounts (typically, 150 mg in stock).

Following the success since 2012 the collaboration with Sanofi aiming at finding of new valuable hit series in most challenging screening campaigns has been extended.
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