Set of Carbamoylimidazoles
Substituted ureas are drawing considerable attention as pharmacologically relevant compounds. Our proprietary trifluorourethanes, reported earlier, are suitable precursors for the preparation of aryl/heteroaryl-alkyl or aryl/heteroaryl-dialkyl urea derivatives via parallel synthesis, but they are not appropriate for the preparation of ureas bearing different alkyl substituents. We report now a new set of building blocks, carbamoylimidazoles, specifically designed for the synthesis of ureas with multiple alkyl groups.